cbd oil spray

The Best CBD Sprays

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Cannabidiol (CBD) is an active ingredient in the cannabis plant that’s making its appearance in an incredible array of products. That’s because beyond its therapeutic benefits, CBD has no intoxicating properties, so you don’t experience the “high” associated with tetrahydrocannabinol (THC).

If you’re interested in trying CBD, you might consider a CBD spray. To help you get started, we found seven worth trying. Read on for our top picks and how to choose one.

CBD sprays can be used in a few different ways. Some are designed to mist directly onto the skin. Some are sprayed into the mouth for oral intake.

The right method of application will depend on the spray itself. But keep in mind that CBD sprays aren’t as popular as other forms of CBD, like gummies or oils, so they can be a little harder to find.

Before you try a CBD spray, it’s important to know how to choose a quality product. We compiled our list by zeroing in on products that meet specific criteria for safety, quality, and company transparency.

Every product listed here:

  • is made by a company that provides proof of third-party testing by an independent lab
  • is made with U.S.-grown hemp
  • contains no more than 0.3 percent THC, according to the certificate of analysis (COA)
  • passes tests for pesticides, heavy metals, and molds, according to the COA

We also considered:

  • company certifications and manufacturing processes
  • product potency
  • overall ingredients
  • indicators of user trust and brand reputation, such as:
    • customer reviews
    • whether the company has been subject to a Food and Drug Administration (FDA) warning letter
    • whether the company makes any unsupported health claims

Pricing guide

  • $= under $25
  • $$ = $25–$50
  • $$$ = over $50

Reliva CBD Wellness CBD Oral Spray

  • CBD type : Isolate
  • CBD potency : 300 mg per bottle, 9 mg per 0.14-mL spray
  • COA :Available online

Price: $

Designed to be sprayed directly into the mouth, this CBD spray is handy when you’re on the go. It’s flavored with peppermint essential oil and made with CBD isolate, which means it doesn’t contain any other cannabis compounds besides CBD.

All Reliva CBD Wellness products are made from traditionally grown U.S. hemp, and the company has built a reputation for excellence as a health and wellness company. COAs are readily available by batch number or product name here.

Reliva CBD Wellness doesn’t ship their products to several states. Visit their website for a full list.

PureKana CBD Oral Spray, Peppermint

  • CBD type : Full-spectrum
  • CBD potency : 180 mg per bottle, 2 mg per spray
  • COA : Available on product page

Price: $$

PureKana’s CBD spray is another peppermint-flavored option that’s sprayed into the mouth. It contains vitamins D and K2 for additional therapeutic benefits. This spray is made with full-spectrum CBD, which means there are trace amounts of THC. It may offer benefits from the entourage effect, a theory about the synergy between different cannabinoids.

PureKana’s 13.5-milliliter (mL) spray bottle is designed to deliver accurate, pre-measured amounts of CBD with each spray. COAs are available by batch number via the product page.

Elate CBD Better Sleep Spray

  • CBD type : Broad-spectrum
  • CBD potency : 300 mg per 30-mL bottle
  • COA : Available on product page

Price: $$$

This tropical-flavored oral sleep spray has 300 mg of water-soluble, nano-emulsified CBD, as well as melatonin, which may help you fall asleep. Though research on nano CBD is limited, some suggests that your body is better able to absorb it than non-nano CBD.

The CBD used in this product is broad-spectrum, which means it contains other cannabinoids besides CBD, but it doesn’t contain any THC.

Elate products are made with organically grown Oregon hemp. COAs are accessible from the product page on the company website.

As of February 2020, Elate was testing their final products for contaminants like molds, pesticides, and heavy metals. However, their newer COAs don’t have this information. It’s best to reach out to the company to get a current, comprehensive COA before making a purchase.

PlusCBD Spray, Peppermint

Use code “healthline25” for 25% off

  • CBD type : Full-spectrum
  • CBD potency : 100 mg per 1-oz. bottle, 1 mg per 2 sprays
  • COA : Available on product page

Price: $

As another full-spectrum spray, PlusCBD delivers additional cannabinoids in every spray so you benefit from the entourage effect.

This particular oral spray is flavored with peppermint oil, but it’s also available in unflavored and cafe mocha varieties. It’s made with hemp grown from EU-certified hemp seeds and extracted with carbon dioxide, a method that ensures no solvents remain.

COAs for the spray are available directly from the product page.

CBD for Life Topical Spray

  • CBD type : Isolate
  • CBD potency : 100 mg per 120-mL bottle
  • COA :Available online

Price: $$

The topical spray is designed to be sprayed directly on areas of discomfort, tension, or tightness. It absorbs quickly, so there’s no need to rub it in. Ingredients like arnica, camphor, and menthol offer anti-inflammatory benefits and a cooling sensation for quick relief.

This spray is also free of GMOs, parabens, phthalates, formaldehyde, and artificial coloring. It’s made with hemp grown in Colorado at a U.S. Department of Agriculture certified organic farm that uses sustainable farming practices.

COAs are available here.

CBDMEDIC Muscle & Joint Pain Relief Spray

Use code “HEALTH15” for 15% off

  • CBD type : Broad-spectrum
  • CBD potency : 200 mg per 50-mL bottle
  • COA : Available by email

Price: $$

CBDMEDIC, a part of the Charlotte’s Web family of topical products, combines hemp extract with other active ingredients for natural pain relief.

This pain relief spray is easy to use and quick to dry, with hemp extract, menthol, and camphor to quickly reduce sore joints and muscles.

COAs are available by email from Charlotte’s Web.

Vertly CBD Infused Cooling Recovery Body Spray

  • CBD type : Full-spectrum
  • CBD potency : 130 mg per bottle
  • COA : Available on product page

Price: $$

Vertly’s cooling spray uses full-spectrum CBD extracted from organic, U.S.-grown hemp plants, as well as peppermint menthol and comfrey extract to relieve pain and inflammation. This spray also includes aloe vera, so it can be used to soothe sunburned skin.

Spray two to four pumps on tired muscles after a hard workout or a long day to ease tightness with immediate cooling relief.

Lab results are readily available on the product page. However, the labs posted only contain cannabinoid and potency information. Though the CBD used to make the product is tested for contaminants, the final product is not.

Purchasing CBD products isn’t like shopping for other over-the-counter wellness products. Since the FDA doesn’t regulate CBD in the same way as drugs or supplements, it’s important to do your homework before making a purchase.

The safest CBD products will come with current, comprehensive COAs from reputable third-party labs. You should be able to find them online easily, or the company should have no problem providing them upon request. Note that making a purchase shouldn’t be the only way you can get access to a product’s COA.

Make a habit of scanning COAs prior to purchase so you can confirm details like potency, the cannabinoid profile (or how much CBD or THC a product has), and whether there’s any evidence of contaminants like heavy metals, molds, or pesticide residue.

Look for a company that’s upfront about where they source their hemp, their cultivation processes, their ingredients, and their product potency. You can also check a company’s reputation by looking for FDA warning letters and lawsuits.

Finally, take a look at customer reviews. If you see bad reviews, pay attention to the complaints shared. It could be a sign to steer clear of a particular brand.

CBD sprays can be used topically or orally. Topical CBD sprays are sprayed directly onto the affected area. In most cases, you won’t need to rub them in. Oral CBD sprays are sprayed into the mouth.

Nasal CBD sprays are not currently recommended by the cannabis community.

No matter how your CBD spray is taken or applied, it’s a good idea to read the directions before using it. There will be a recommended dosage, and it’s always wise to start with the lowest dose so you can gauge your body’s response. Our CBD dosage guide is a good reference point if you’re new to CBD.

While CBD is generally considered safe and helpful for various conditions, there is research that suggests some people may experience side effects. These can include:

  • fatigue
  • diarrhea
  • changes in appetite or weight

If you’re using a topical CBD spray, try a small test patch first to see how your body responds. You should also avoid using it on broken skin to avoid irritation.

Before trying any CBD products, it’s smart to speak with your doctor first. That’s particularly wise if you’re currently taking any medications, as there can be interactions.

A CBD spray may be a great way to experiment with CBD products that are both convenient and effective. Just remember to research your options first. Look for a product that comes from a reputable brand that tests its products for potency and contaminants.

Is CBD Legal? Hemp-derived CBD products (with less than 0.3 percent THC) are legal on the federal level, but are still illegal under some state laws. Marijuana-derived CBD products are illegal on the federal level, but are legal under some state laws. Check your state’s laws and those of anywhere you travel. Keep in mind that nonprescription CBD products are not FDA-approved, and may be inaccurately labeled.

Jessica Timmons has been working as a freelance writer since 2007, covering everything from pregnancy and parenting to cannabis, chiropractic, stand-up paddling, fitness, martial arts, home decor, and much more. Her work has appeared in mindbodygreen, Pregnancy & Newborn, Modern Parents Messy Kids, and Coffee + Crumbs. See what she’s up to now at

Last medically reviewed on October 27, 2020

CBD sprays are a great way to take CBD orally or topically. Get our best CBD spray recommendations and learn how to choose one.

What to know about CBD oral sprays

Cannabidiol (CBD) is an increasingly popular ingredient for people seeking alternative remedies for various conditions, including chronic pain. CBD comes in the form of oral sprays, as well as edibles and topical products.

Cannabis plants contain compounds called cannabinoids. The two best-known cannabinoids are tetrahydrocannabinol (THC) and CBD.

THC can lead to psychological effects and the “high” that people frequently associate with cannabis. CBD, however, does not produce the same psychoactive effects. It might, on the other hand, have numerous potential health benefits.

Various forms of CBD exist, including oils, gummies, topicals, and oral sprays. However, it is important to note that availability may vary from state to state, and that it is currently illegal to sell CBD food products or dietary supplements. People can learn more about the regulation of CBD products here.

Keep reading to learn more about the effects and potential benefits of CBD oral sprays. This article also covers how this form of CBD compares with others that are available.

Share on Pinterest CBD oral sprays are faster-acting than CBD edibles, such as gummies.

CBD products are available in many forms, including oral sprays.

Sprays involve a tincture of CBD extract and ethanol alcohol. The alcohol helps extract the cannabinoids. An oral spray dispenses directly into the mouth, either under the tongue or inside the cheek.

Although the research into CBD’s use as a remedy for various conditions is ongoing, studies that support CBD’s purported benefits are currently limited.

The following conditions may benefit from CBD use.


There are anecdotal reports of people who use CBD experiencing anxiety-reducing effects. CBD may also help counteract the anxiety-producing effects linked to high levels of THC.

However, existing studies into the effects of CBD on anxiety involve only small groups of participants. Further research may help clarify the potential link between the two.

Chemotherapy side effects

People undergoing chemotherapy for cancer may experience nausea and vomiting. Doctors usually prescribe antiemetics to counteract these unpleasant side effects.

A 2018 study found that CBD limited a surge of serotonin levels in the interoceptive insular cortex (IIC) of rats that received injections of a nausea-inducing chemical compound.

The IIC region of the human brain is responsible for nausea. Therefore, the findings suggest that it may be possible for scientists to develop a CBD-based antinausea treatment for people receiving chemotherapy treatment.

One 2019 review also suggests that cannabinoids may help prevent other adverse effects associated with chemotherapy, including poor appetite and pain. That said, the evidence in this area is weak.

Chronic pain

There is evidence to suggest that cannabinoids may help with pain relief, but few studies exist on CBD specifically.

A 2018 review took into account 48 studies on using cannabinoids and cannabis for the relief of chronic non-cancer-related pain.

The authors suggest that there is moderate evidence pointing to the pain-relieving effects of cannabinoids compared with a placebo. However, people using cannabinoids were also more likely to experience adverse effects than those taking the placebo.

A more recent study analyzed the evidence surrounding the benefits and harms of medical cannabinoids in the treatment of chronic non-cancer-related pain. At 2 weeks, there was “moderate evidence” to support the use of cannabinoids in treating this type of pain.

A 2019 review supports the use of a combined THC and CBD oral spray called nabiximols (Sativex) for multiple sclerosis-related pain. However, the Food and Drug Administration (FDA) have not yet approved this spray for use.

One randomized controlled trial from 2020 suggests a link between topical cannabidiol oil and relief from peripheral neuropathy-related pain. However, the study only looked into topical CBD use, not the use of oral sprays.

Although current evidence does not fully support the use of CBD for relief from chronic pain, new research and clinical trials are on the horizon. For example, the National Center for Complementary and Integrative Health are funding further research on the subject.


Currently, the FDA have only approved a single drug containing CBD. Epidiolex is a treatment option for severe forms of epilepsy called Dravet syndrome and Lennox-Gastaut syndrome.

Clinical trials found that when people with these conditions take Epidiolex with other seizure drugs, they experience fewer seizures than those taking a placebo in addition to seizure medications.

However, there has been little research into the benefits of CBD for milder, more common forms of epilepsy.


Limited evidence suggests that CBD may help people with substance abuse disorder by curbing compulsive behaviors.

A 2018 animal study found that CBD reduced relapse in rats for 5 months.

One study from 2019 found that CBD may help people with heroin use disorder by reducing cravings and anxiety.

Some studies also suggest that CBD may help people with post-traumatic stress disorder by reducing insomnia and nightmares.

Although this preliminary research is encouraging, more studies are necessary to establish conclusive evidence.

For more information and resources on CBD and CBD products, please visit our dedicated hub.

This article will examine the effects and potential benefits of cannabidiol (CBD) oral spray and compare it with other available forms of CBD.